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Recombinant Mouse CCL1 Protein (Fc Tag)

Product Specifications

Background

Mouse TCA-3 is a member of the CC beta family of chemokines. The Human chemokine I-309, which shares approximately 42% amino acid (aa) sequence identity, has been assumed to be the homologue of Mouse TCA-3. Mouse TCA-3 and Human I-309 also share significant sequence homology in the 5' flanking region of their genes and each contain an extra pair of cysteine residues not found in most other chemokines.

Abbreviation

CCL1

Synonyms

C-C motif chemokine 1; Ccl1; CCL1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; Small-inducible cytokine A1; T lymphocyte secreted protein I-309; T lymphocyte secreted protein I-309; T lymphocyte-secreted protein I-309; TCA3

UniProt

P10146

Accession Number

P10146

Expression System

Mammalian

Tag

C-Fc

Sequence

Lys24-Cys92

Field of Research

Immunology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

32.5 kDa

Observed Molecular Weight

35-40 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Mouse

Available Sizes

Frequently Asked Questions

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