Recombinant Mouse CD200 Protein (Fc Tag)
Product Specifications
Background
Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion. Involved in negative regulation of cell population proliferation, negative regulation of macrophage activation, and negative regulation of neuroinflammatory response. Located in cell surface. Is expressed in several structures, including anterior naris, aorta, bone, nervous system, and retina. Used to study autoimmune disease. Orthologous to human CD200 (CD200 molecule) .
Abbreviation
CD200
Synonyms
Antigen identified by monoclonal MRC OX 2; CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G
UniProt
O54901
Accession Number
O54901
Expression System
Mammalian
Tag
C-Fc
Sequence
Gln31-Gly232
Field of Research
Cardiovascular; Immunology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
47.1 kDa
Observed Molecular Weight
60 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
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