Recombinant Mouse CD200 Protein (Fc Tag)

Product Specifications

Background

Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion. Involved in negative regulation of cell population proliferation, negative regulation of macrophage activation, and negative regulation of neuroinflammatory response. Located in cell surface. Is expressed in several structures, including anterior naris, aorta, bone, nervous system, and retina. Used to study autoimmune disease. Orthologous to human CD200 (CD200 molecule) .

Abbreviation

CD200

Synonyms

Antigen identified by monoclonal MRC OX 2; CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G

UniProt

O54901

Accession Number

O54901

Expression System

Mammalian

Tag

C-Fc

Sequence

Gln31-Gly232

Field of Research

Cardiovascular; Immunology

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.