Recombinant Human DKK-3 Protein (His Tag)

DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1 , DKK2 , DKK3 and DKK4. It is a secreted protein , and also known as REIC (Reduced Expansion in Immortalized Cells) . The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

UNQ; PRO; Dickkopf-Related Protein; hDkk; Dickkopf; DKK; DKK3; REIC; RIG; Dickkopf-3; Dickkopf-Related Protein 3; Dkk-3; hDkk-3; UNQ258; PRO295; Dickkopf 3; Dickkopf 3 homolog; Dickkopf 3 homolog (Xenopus laevis) ; Dickkopf homolog 3; Dickkopf related protein 3; Dickkopf related protein 3 Precursor; Dickkopf WNT signaling pathway inhibitor 3; Dickkopf3; DKK 3; hDkk 3; hDkk3; homolog of; Regulated in glioma; RIG-like 5-6; RIG-like 7-1; Xenopus

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.