Recombinant Human PTX3 Protein (Fc Tag)
Product Specifications
Background
Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.
Abbreviation
PTX3
Synonyms
AI607804; Pentaxin 3; Pentaxin-related protein PTX3; Pentraxin 3 long; Pentraxin-related gene; Pentraxin-related gene rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14
UniProt
P26022
Accession Number
P26022
Expression System
Mammalian
Tag
C-Fc
Sequence
Glu18-Ser381
Field of Research
Cancer; Cardiovascular; Immunology
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
64.9 kDa
Observed Molecular Weight
60-80 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Documents
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![ZNF329 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B11]](https://cdn.genprice.uk/products/937/6868c3f4994c49e6dc402bf7/imageurl/ta809583am.webp)
TA809583AM 100 µL
ZNF329 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B11]
Sign In for Pricing
View Details 
BNC041943-100 1x 100 µL
TIMP1 (Colorectal Cancer Biomarker / Marker of Lymph Node Metastasis) (rTIMP1/1710), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
E-UNEL-M0140-01 5x 96 Tests
Uncoated Mouse ST2 (Growth stimulation expressed gene 2) ELISA Kit
Sign In for Pricing
View Details E-UNEL-M0140-02 15x 96 Tests
Uncoated Mouse ST2 (Growth stimulation expressed gene 2) ELISA Kit
Sign In for Pricing
View Details 