Recombinant Human ICAM5 Protein (His Tag)
Product Specifications
Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Abbreviation
ICAM5
Synonyms
ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5; telencephalin; Telencephalin; TLCN; TLN
UniProt
Q9UMF0
Accession Number
Q9UMF0
Expression System
Mammalian
Tag
C-His
Sequence
Glu32-Trp835
Field of Research
Neuroscience; Tags & Cell Markers
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/prrlqd
Product MSDS
https://789.bio/eb/H0RRRC
Calculated Molecular Weight
88.3 kDa
Observed Molecular Weight
100-120 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Curated Selection
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