Recombinant Human MAG Protein (Fc Tag)
Product Specifications
Background
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Abbreviation
MAG
Synonyms
GMA; MAG; MAG; Myelin associated glycoprotein; Myelin-associated glycoprotein; S MAG; S-MAG; Sialic acid binding Ig like lectin 4A; Sialic acid binding immunoglobulin like lectin 4A; Siglec 4a; Siglec-4a; SIGLEC4A; SPG75
UniProt
P20916
Accession Number
P20916
Expression System
Mammalian
Tag
C-Fc
Sequence
Gly20-Pro516
Field of Research
Neuroscience
Endotoxin
< 1.0 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
79.5 kDa
Observed Molecular Weight
80-100 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
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