Recombinant Mouse CXCL1/Lymphotactin1/I-TAC Protein (Trx Tag)

Product Specifications

Background

I-TAC, also known as CXCL1/Lymphotactin1/I-TAC, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL1/Lymphotactin0. I-TAC is chemotactic for activated T cells. The CXCL1/Lymphotactin1/I-TAC gene is located on human chromosome 4 along with many other members of the CXC chemokine family.

Abbreviation

CXCL1/Lymphotactin1/I-TAC

Synonyms

B-R; ENA; Epithelial Neutrophil Activating Peptide; AMCF; AMCF-II; b-R1; Cxcl; Cxcl6; ENA-78; Epithelial Neutrophil Activating Peptide-78; H174; IP9; IP-9; LIX; Scyb; Scyb5; Scyb6; SCYB9B; Scyb11; Cxcl11

UniProt

Q9JHH5

Accession Number

Q9JHH5

Expression System

E.coli

Tag

N-Trx

Sequence

Phe22-Met100

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.