Recombinant Mouse CCL3/MIP-1α Protein (Trx Tag)

Product Specifications

Background

CCL3/MIP-1α is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. All chemokines contain four conserved cysteines linked by disulfide bonds, and two major subfamilies, namely CXC and CC, are defined on the basis of the first two cysteines which are separated by one amino acid or are adjacent. CCL3/MIP-1α is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.

Abbreviation

CCL3/MIP-1α

Synonyms

CCL; Scya; C-C motif chemokine; chemokine (C-C motif) ligand; G0S19; C-C motif chemokine 3; chemokine (C-C motif) ligand 3; G0S19-1; Heparin-binding chemotaxis protein; LD78 alpha; LD78a; LD78ALPHA; Macrophage inflammatory protein 1-alpha; MIP-1 alpha; MIP1-a; MIP-1-alpha; Mip1a; Scya3; Ccl3

UniProt

P10855

Accession Number

P10855

Expression System

E.coli

Tag

N-Trx

Sequence

Ala24-Ala92

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.