Recombinant Mouse CCL6/C10 Protein (Trx Tag)
Product Specifications
Background
In mice , CCL6/C10 is expressed in cells from neutrophil and macrophage lineages , and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3 , and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However , in activated T cell lines , expression of CCL6/C10 is greatly reduced.CCL6/C10 can also be induced in the Mouse lung by the cytokine interleukin 13
Abbreviation
CCL6/C10
Synonyms
Scya; Chemokine C C motif Ligand; Small Inducible Cytokine A; chemokine (C-C motif) ligand; CCL 6; chemokine (C-C motif) ligand 6; Chemokine C C motif Ligand 6; MRP1; MRP-1; Small Inducible Cytokine A6; C10; Scya6; Ccl6; C10; CCL 6; chemokine (C-C motif) ligand 6; Chemokine C C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6
UniProt
P27784
Accession Number
P27784
Expression System
E.coli
Tag
N-Trx
Sequence
Gly22-Ala116
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
30.3 kDa
Observed Molecular Weight
32 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
Curated Selection
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