Recombinant Mouse IL16 Protein (Trx Tag)

Product Specifications

Background

Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of Mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and Mouse IL-16 share approximately 86% amino acid sequence identity.

Abbreviation

IL16

Synonyms

HGNC:5980; HsT19289; IL-16; IL16; IL16; Interleukin 16 precursor; Interleukin-16; LCF; Lymphocyte chemoattractant factor; Neuronal interleukin 16; NIL16; prIL 16; PrIL16; Prointerleukin 16

UniProt

O54824

Accession Number

O54824

Expression System

E.coli

Tag

N-Trx

Sequence

Ser1205-Ser1322

Field of Research

Cancer; Immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.