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Recombinant Human FGF6 Protein (Sumo Tag)

Product Specifications

Background

FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis. It is also required for normal muscle regeneration. FGF6 gene displayed oncogenic transforming activity when transfected into mammalian cells.

Abbreviation

FGF6

Synonyms

FGF 6; FGF-6; Fgf6; FGF6; Fibroblast growth factor 6; Fibroblast growth factor 6 precursor; HBGF 6; HBGF-6; HBGF6; Heparin secretory-transforming protein 2; Heparin-binding growth factor 6; HST 2; HST-2; HST2; HSTF-2

UniProt

P10767

Accession Number

P10767

Expression System

E.coli

Tag

N-Sumo

Sequence

Gly41-Lle208

Field of Research

Cancer; Cardiovascular; Signal Transduction

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

34.5 kDa

Observed Molecular Weight

34.5 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human

Available Sizes

Frequently Asked Questions

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