Recombinant Human IL17D Protein (Sumo Tag)
Product Specifications
Background
IL17D is a secreted cytokine with homology to the IL-17 family of proteins. IL17D is preferentially expressed in skeletal muscle, brain, adipose tissue, heart, lung, and pancreas. The treatment of endothelial cells with IL17D has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by IL17D was found to be NF-kappa B-dependent.
Abbreviation
IL17D
Synonyms
IL 17D; IL 22; IL 27; IL-17D; IL-27; IL17D; IL17D; IL27; Interleukin 17D; Interleukin 27; Interleukin-17D; Interleukin-27
UniProt
Q8TAD2
Accession Number
Q8TAD2
Expression System
E.coli
Tag
N-Sumo
Sequence
Ala16-Pro202
Field of Research
Immunology; Cancer
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 90% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
33.4 kDa
Observed Molecular Weight
35-40 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
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