IRAK4-IN-1
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
Product Specifications
CAS Number
[1820787-94-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
IRAK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/IRAK4-IN-1.html
Purity
99.62
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
N#CC1=CC2=C(N=CN=C2N[C@@H]3CC[C@@H](N4CCOCC4)CC3)C=C1
Molecular Formula
C19H23N5O
Molecular Weight
337.42
Precautions
H315, H319, H335
References & Citations
[1]Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med Chem Lett. 2017 Jun 15;27 (12) :2721-2726.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRAK4
Available Sizes
Curated Selection
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