What is the catalog number for Perflubron?

The catalog number for Perflubron is HY-B1724.

What sizes are available for Perflubron?

Perflubron is available in the following size(s): 1 g, 10 mM - 1 mL.

How many pack sizes does Perflubron come in?

Perflubron is available in 2 different pack sizes.

Is Perflubron in stock?

Perflubron is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Perflubron?

Perflubron is manufactured by QuantiMol.

What is the estimated delivery time for Perflubron?

Estimated delivery time for Perflubron is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Perflubron?

The safety data sheet for Perflubron is available here: http://file.medchemexpress.com/batch_PDF/HY-B1724/Perflubron-SDS-MedChemExpress.pdf.

Perflubron

Perflubron (Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Perflubron inhibits chemokine expression and NF-κB activation. Perflubron can be emulsified with egg phospholipids (EYP) and shows exceptionally fast excretion characteristics. Perflubron has anti-inflammatory, antiviral and cytoprotective effects[1][2][3][4][5][6][7].

Product Specifications

CAS Number

423-55-2

Product Name Alternative

Perfluorooctyl bromide; 1-Bromoperfluorooctane; PFOB

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

NF-κB; RSV

Type

Reference compound

Related Pathways

Anti-infection; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Infection; Inflammation/Immunology

Concentration

10mM

Purity

99.98

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(Br)F

Molecular Formula

C8BrF17

Molecular Weight

498.96

Precautions

H302, H315, H319, H335

References & Citations

[1]Perflubron, From Wikipedia, the free encyclopedia|[2]Perflubron|[3]Woods CM, et al. Perflubron attenuates neutrophil adhesion to activated endothelial cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2000 May;278 (5) :L1008-17.|[4]Babu PB, et al. Hyperoxia-induced changes in human airway epithelial cells: the protective effect of perflubron. Pediatr Crit Care Med. 2005 Mar;6 (2) :188-94.|[5]Kishioka C, et al. Perfluorooctyl bromide (perflubron) stimulates mucin secretion in the ferret trachea. Chest. 1999 Mar;115 (3) :823-8.|[6]Haeberle HA, et al. Perflubron reduces lung inflammation in respiratory syncytial virus infection by inhibiting chemokine expression and nuclear factor-kappa B activation. Am J Respir Crit Care Med. 2002 May 15;165 (10) :1433-8.|[7]Weiss DJ, et al. Perflubron enhances adenovirus-mediated gene expression in lungs of transgenic mice with chronic alveolar filling. Hum Gene Ther. 1999 Sep 20;10 (14) :2287-93.|[8]Weiss DJ, et al. Use of perflubron to enhance lung gene expression: safety and initial efficacy studies in non-human primates. Mol Ther. 2002 Jan;5 (1) :8-15.