Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SMANT (hydrochloride)

SMANT hydrochloride is a Smoothened (Smo) signaling inhibitor. SMANT hydrochloride is antagonist of Smo accumulation within the primary cilium (PC) . SMANT hydrochloride has an equivalent activity in inhibiting SmoM2 (oncogenic form of Smo) and wild-type Smo[1].

Product Specifications

CAS Number

1177600-74-6

UNSPSC

12352005

Hazard Statement

H302-H361-H372-H410

Target

Hedgehog; Smo

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/smant-hydrochloride.html

Purity

99.90

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=C(Br)C=C1)CCN2CC(C)CC(C)C2.[H]Cl

Molecular Formula

C16H24BrClN2O

Molecular Weight

375.73

Precautions

P260-P264-P270-P273-P280-P330-P391-P405-P501

References & Citations

[1]Wang Y, et al. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15;7 (6) :1040-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Slc4a8 Mouse Gene Knockout Kit (CRISPR)
KN516147 1 Kit

Slc4a8 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Mouse CamL activation kit by CRISPRa
GA200508 1 Kit

Mouse CamL activation kit by CRISPRa

Sign In for Pricing
View Details
2,7-Dibromonapthalene
TRC-D425760-250MG 250 mg

2,7-Dibromonapthalene

Sign In for Pricing
View Details
Ɑ-Hydroxy-ω-Azido PEG
1320000-00-5.500MG 500 mg

Ɑ-Hydroxy-ω-Azido PEG

Sign In for Pricing
View Details
NNMT Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3D8]
TA502624BM 100 µL

NNMT Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3D8]

Sign In for Pricing
View Details
Mouse Gdap2 activation kit by CRISPRa
GA201576 1 Kit

Mouse Gdap2 activation kit by CRISPRa

Sign In for Pricing
View Details