Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SMANT (hydrochloride)

SMANT hydrochloride is a Smoothened (Smo) signaling inhibitor. SMANT hydrochloride is antagonist of Smo accumulation within the primary cilium (PC) . SMANT hydrochloride has an equivalent activity in inhibiting SmoM2 (oncogenic form of Smo) and wild-type Smo[1].

Product Specifications

CAS Number

1177600-74-6

UNSPSC

12352005

Hazard Statement

H302-H361-H372-H410

Target

Hedgehog; Smo

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/smant-hydrochloride.html

Purity

99.90

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=C(Br)C=C1)CCN2CC(C)CC(C)C2.[H]Cl

Molecular Formula

C16H24BrClN2O

Molecular Weight

375.73

Precautions

P260-P264-P270-P273-P280-P330-P391-P405-P501

References & Citations

[1]Wang Y, et al. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. ACS Chem Biol. 2012 Jun 15;7 (6) :1040-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

AKR1B1 (NM_001628) Human Over-expression Lysate
LY419838 100 µg

AKR1B1 (NM_001628) Human Over-expression Lysate

Sign In for Pricing
View Details
5R-Rimegepant
TRC-R790310-25MG 25 mg

5R-Rimegepant

Sign In for Pricing
View Details
Human DRIM (UTP20) activation kit by CRISPRa
GA109132 1 Kit

Human DRIM (UTP20) activation kit by CRISPRa

Sign In for Pricing
View Details
P Glycoprotein (ABCB1) (262-277) Rabbit Polyclonal Antibody
AP07398PU-N 50 µg

P Glycoprotein (ABCB1) (262-277) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Ubxn11 Mouse Gene Knockout Kit (CRISPR)
KN518630 1 Kit

Ubxn11 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
CHL1 Rabbit Polyclonal Antibody
TA374743 100 µL

CHL1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details