Recombinant PMVK/phosphomevalonate kinase Monoclonal Antibody
Product Specifications
Background
This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 2-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.
Abbreviation
PMVK
UniProt
Q15126
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human PMVK / phosphomevalonate kinase Protein
Target
POROK; OTTHUMP; PMVK; HUMPMKI; PMK; PMKA; PMKASE; POROK1; hPMK; OTTHUMP00000035546; Phosphomevalonate kinase; PMK PEN; PMKPEN; PMKI
Clonality
Monoclonal
Clone
14B11
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/6fptoz8w
Product MSDS
https://789.bio/eb/r4Nhx1AG
Calculated Molecular Weight
21 kDa
Observed Molecular Weight
21 kDa
Isotype
IgG
Curated Selection
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