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Recombinant PMVK/phosphomevalonate kinase Monoclonal Antibody

Product Specifications

Background

This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 2-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.

Abbreviation

PMVK

UniProt

Q15126

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human PMVK / phosphomevalonate kinase Protein

Target

POROK; OTTHUMP; PMVK; HUMPMKI; PMK; PMKA; PMKASE; POROK1; hPMK; OTTHUMP00000035546; Phosphomevalonate kinase; PMK PEN; PMKPEN; PMKI

Clonality

Monoclonal

Clone

14B11

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

21 kDa

Observed Molecular Weight

21 kDa

Isotype

IgG

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