Recombinant ECH1 Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,1-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Abbreviation
ECH1
UniProt
Q13011
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human ECH1 Protein
Target
ECH; Delta;5) -Delta; ECH1; HPXEL;4) -dienoyl-CoA isomerase;5) -Delta (2; Delta (3; mitochondrial; Delta (3 5) Delta (2 4) dienoyl CoA isomerase; Delta (3 5) Delta (2 4) dienoyl CoA isomerase mitochondrial; Delta3 5 delta2 4 dienoyl CoA isomerase; Dienoyl CoA isomerase; ECH 1; Enoyl Coenzyme A hydratase 1; Enoyl Coenzyme A hydratase 1 peroxisomal; MS1034; Peroxisomal enoyl CoA hydratase 1; Peroxisomal enoyl coenzyme A hydratase like protein
Clonality
Monoclonal
Clone
14B7
Conjugation
Unconjugated
Applications
WB
Field of Research
Tags & Cell Markers; Signal Transduction; Cardiovascular; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/mcotjzah
Product MSDS
https://789.bio/eb/XccJ0QDc
Calculated Molecular Weight
36 kDa
Observed Molecular Weight
36 kDa
Isotype
IgG
Curated Selection
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