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Recombinant ECH1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,1-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Abbreviation

ECH1

UniProt

Q13011

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human ECH1 Protein

Target

ECH; Delta;5) -Delta; ECH1; HPXEL;4) -dienoyl-CoA isomerase;5) -Delta (2; Delta (3; mitochondrial; Delta (3 5) Delta (2 4) dienoyl CoA isomerase; Delta (3 5) Delta (2 4) dienoyl CoA isomerase mitochondrial; Delta3 5 delta2 4 dienoyl CoA isomerase; Dienoyl CoA isomerase; ECH 1; Enoyl Coenzyme A hydratase 1; Enoyl Coenzyme A hydratase 1 peroxisomal; MS1034; Peroxisomal enoyl CoA hydratase 1; Peroxisomal enoyl coenzyme A hydratase like protein

Clonality

Monoclonal

Clone

14B7

Conjugation

Unconjugated

Applications

WB

Field of Research

Tags & Cell Markers; Signal Transduction; Cardiovascular; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://789.bio/ea/mcotjzah

Product MSDS

https://789.bio/eb/XccJ0QDc

Calculated Molecular Weight

36 kDa

Observed Molecular Weight

36 kDa

Isotype

IgG

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