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Recombinant Fragile histidine triad/FHIT Monoclonal Antibody

Product Specifications

Background

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 0, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Abbreviation

FHIT

UniProt

P49789

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Fragile histidine triad / FHIT Protein

Target

FHIT; AP3Aase; FRA3B; AP3A hydrolase; AP3A hydrolase fragile site 3p14.2; Bis 5' adenosyl triphosphatase; Bis (5' adenosyl) triphosphatase; Diadenosine 5' 5''' P1 P3 triphosphate hydrolase; Dinucleosidetriphosphatase; FRA 3B; Fragile histidine triad; Fragile histidine triad gene; Fragile histidine triad protein; Tumor suppressor protein

Clonality

Monoclonal

Clone

14B3

Conjugation

Unconjugated

Applications

WB; ICC/IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; ICC/IF 1:20-1:100

Buffer

0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

17 kDa

Observed Molecular Weight

20 kDa

Isotype

IgG

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