Recombinant Fragile histidine triad/FHIT Monoclonal Antibody
Product Specifications
Background
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 0, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Abbreviation
FHIT
UniProt
P49789
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Fragile histidine triad / FHIT Protein
Target
FHIT; AP3Aase; FRA3B; AP3A hydrolase; AP3A hydrolase fragile site 3p14.2; Bis 5' adenosyl triphosphatase; Bis (5' adenosyl) triphosphatase; Diadenosine 5' 5''' P1 P3 triphosphate hydrolase; Dinucleosidetriphosphatase; FRA 3B; Fragile histidine triad; Fragile histidine triad gene; Fragile histidine triad protein; Tumor suppressor protein
Clonality
Monoclonal
Clone
14B3
Conjugation
Unconjugated
Applications
WB; ICC/IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; ICC/IF 1:20-1:100
Buffer
0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
17 kDa
Observed Molecular Weight
20 kDa
Isotype
IgG
Curated Selection
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