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Recombinant ASGR2/ASGPR2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Abbreviation

ASGR2

UniProt

P07307

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human ASGR2 / ASGPR2 protein

Target

ASGR; ASGPR; ASGP-R; CLEC4H; ASGR2; ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2

Clonality

Monoclonal

Clone

12B10

Conjugation

Unconjugated

Applications

IHC-P; FCM; ICC/IF

Field of Research

Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500; ICC/IF 1:20-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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