Recombinant ASGR2/ASGPR2 Monoclonal Antibody
Product Specifications
Background
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abbreviation
ASGR2
UniProt
P07307
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human ASGR2 / ASGPR2 protein
Target
ASGR; ASGPR; ASGP-R; CLEC4H; ASGR2; ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2
Clonality
Monoclonal
Clone
12B10
Conjugation
Unconjugated
Applications
IHC-P; FCM; ICC/IF
Field of Research
Signal Transduction
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500; ICC/IF 1:20-1:100; FCM 1:25-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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