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Recombinant CLPS/Colipase Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.

Abbreviation

CLPS

UniProt

P04118

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CLPS / Colipase protein

Target

CLPS; colipase; COL; Colipase pancreatic; Pancreatic colipase preproprotein

Clonality

Monoclonal

Clone

12B9

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Cardiovascular; Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:250-1:1000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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