Recombinant MAX/MYC associated factor X Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 4. Alternative splicing results in multiple transcript variants.
Abbreviation
MAX
UniProt
P61244
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human MAX / MYC associated factor X protein
Target
BHLHd; MAX; bHLHd4; Class D Basic Helix-Loop-Helix Protein 4; Myc-Associated Factor X; Protein Max
Clonality
Monoclonal
Clone
11B4
Conjugation
Unconjugated
Applications
WB; FCM; ICC/IF; IP
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; FCM 1:100-1:500; ICC/IF 1:100-1:500; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
20 kDa
Isotype
IgG
Curated Selection
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