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Recombinant PARK7/DJ-1 Monoclonal Antibody

Product Specifications

Background

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 4. Two transcript variants encoding the same protein have been identified for this gene.

Abbreviation

PARK7

UniProt

Q99497

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human PARK7 / DJ-1 protein

Target

GATD; PARK; DJ-1; DJ1; GATD2; HEL-S-67p; PARK7

Clonality

Monoclonal

Clone

11A6

Conjugation

Unconjugated

Applications

WB; FCM; ICC/IF; IP

Field of Research

Neuroscience; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000; FCM 1:25-1:100; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20 kDa

Observed Molecular Weight

20 kDa

Isotype

IgG

Available Sizes

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