Recombinant PARK7/DJ-1 Monoclonal Antibody
Product Specifications
Background
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 4. Two transcript variants encoding the same protein have been identified for this gene.
Abbreviation
PARK7
UniProt
Q99497
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human PARK7 / DJ-1 protein
Target
GATD; PARK; DJ-1; DJ1; GATD2; HEL-S-67p; PARK7
Clonality
Monoclonal
Clone
11A6
Conjugation
Unconjugated
Applications
WB; FCM; ICC/IF; IP
Field of Research
Neuroscience; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; FCM 1:25-1:100; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
20 kDa
Observed Molecular Weight
20 kDa
Isotype
IgG
Available Sizes
Curated Selection
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