Recombinant RANKL Monoclonal Antibody
Product Specifications
Background
TNF-related activation-induced cytokine (TRANCE; also RANKL, OPGL, and ODF) is a 35 kDa (predicted) type II transmembrane glycoprotein and member of the TNF cytokine family. Human TRANCE is 317 amino acids (aa) in length and contains a 47 aa cytoplasmic region, a 21 aa transmembrane region, and a 249 extracellular domain (ECD), which contains two potential sites of N-linked glycosylation.
Abbreviation
TNFSF11
UniProt
O14788
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human RANKL Protein
Target
OPTB; tumor necrosis factor ligand superfamily member; TNFSF; hRANKL; TNFSF11; CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf; Osteoclast differentiation factor; Receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor ligand superfamily member 11; RANKL; TNFSF11; OPGL; TNF superfamily member 11; Tumor necrosis factor superfamily member 11
Clonality
Monoclonal
Clone
5F3
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Cardiovascular
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
37 kDa
Isotype
IgG
Curated Selection
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