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Recombinant Coagulation Factor IX/FIX/F9 Monoclonal Antibody

Product Specifications

Background

Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX/F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX/F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX/F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX/F9 are also the cause of recessive X-linked hemophilia B (HEMB) which also known as Christmas disease.

Abbreviation

F9

UniProt

P00740

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Coagulation Factor IX / FIX / F9 protein

Target

F9p; F9 p; THPH; Coagulation factor; F9; F9 p22; FIX; HEMB; P19; PTC; THPH8; F9p22; Christmas factor; Coagulation factor 9; Coagulation factor IX; Coagulation factor IXa heavy chain; Coagulation factor IXa light chain; Plasma thromboplastin component; Christmas Disease; Coagulant factor IX; FA9; Factor 9; Factor IX Deficiency; FactorIX; Haemophilia B; MGC129641; MGC129642; Plasma Thromboplastic Component

Clonality

Monoclonal

Clone

4F4

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.1-0.5 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

55 kDa

Observed Molecular Weight

55 kDa

Isotype

IgG

Available Sizes

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