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Recombinant Cadherin-17/LI-cadherin/CDH17 Monoclonal Antibody

Product Specifications

Background

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Abbreviation

CDH17

UniProt

Q12864

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Cadherin-17 / LI-cadherin / CDH17 protein

Target

Intestinal Peptide-Associated Transporter HPT; Cadherin; CDH; HPT; CDH17; CDH16; HPT-1; HPT1; Cadherin-17; Intestinal Peptide-Associated Transporter HPT-1; LI-Cadherin; Liver-Intestine Cadherin

Clonality

Monoclonal

Clone

3F10

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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