Recombinant SAA4 Monoclonal Antibody
Product Specifications
Background
SAA4 is a member of the SAA family. SAA proteins are family of apolipoproteins of high density lipoprotein (HDL) . They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90% of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice. It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown, and its serum concentration has no association with those of other major apolipoproteins.
Abbreviation
SAA4
UniProt
P35542
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human SAA4 protein
Target
Amyloid A; C SAA; Constitutively expressed serum amyloid A protein; C-SAA; SAA 4; SAA4 protein; SAA4_HUMAN; serum; Serum amyloid A 4 protein; Serum amyloid A4 constitutive; Serum amyloid A-4 protein; CSAA; SAA4; serum; Constitutively expressed serum amyloid A protein (C-SAA)
Clonality
Monoclonal
Clone
3F8
Conjugation
Unconjugated
Applications
WB; FCM; ICC/IF
Field of Research
Cardiovascular; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; FCM 1:25-1:100; ICC/IF 1:20-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
15 kDa
Observed Molecular Weight
15 kDa
Isotype
IgG
Curated Selection
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