Recombinant Phospho-cdc25C (Ser216) Monoclonal Antibody

Product Specifications

Background

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p50-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.

Abbreviation

CDC25C

UniProt

P30307

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues around Ser216 of the Human Phospho-cdc25C

Target

CDC; PPP1R; CDC25C; CDC25; PPP1R60

Clonality

Monoclonal

Clone

8A7

Conjugation

Unconjugated

Applications

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1000-1:5000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.