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Recombinant CD3d/CD3 delta Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD0 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK) . Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Abbreviation

CD3D

UniProt

P04234

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CD3D protein

Target

IMD; CD3D; CD3-DELTA; IMD19; T3D; T-Cell Receptor T3 Delta Chain; T-cell surface glycoprotein CD3 delta chain; T3; CD3 delta

Clonality

Monoclonal

Clone

9A2

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Immunology; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 1-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20 kDa

Observed Molecular Weight

20 kDa

Isotype

IgG

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