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Recombinant KLK-11/Kallikrein-11 Monoclonal Antibody

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 16. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed.

Abbreviation

KLK11

UniProt

Q9UBX7

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human KLK-11 protein

Target

KLK; UNQ; PRO; PRSS; KLK11; PRSS20; TLSP; UNQ649; PRO1279; Hippostasin; hK11; Kallikrein 11; Kallikrein 11 isoform 1 preproprotein; Kallikrein 11 isoform 2 precursor; Kallikrein 11 precursor; Kallikrein related peptidase 11; Kallikrein-11; Kallikrein-11 inactive chain 2; KLK 11; MGC33060; Protease serine 20 trypsin like; Protease serine trypsin like; Serine protease 20; Trypsin like protease; Trypsin-like protease

Clonality

Monoclonal

Clone

8C7

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Signal Transduction; Cancer; Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

31 kDa

Observed Molecular Weight

49 kDa

Isotype

IgG

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