Recombinant EpCAM/TROP-1/TACSTD1 Monoclonal Antibody
Product Specifications
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Abbreviation
EpCAM
UniProt
P16422
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human EpCAM protein
Target
M4S; MIC; M1S; DIAR; TROP; HNPCC; GA733; TACSTD; EGP; EPCAM; DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1; Ep-CAM; epithelial cell adhesion molecule; GA733-2; M1S2; MK-1; KSA; EGP40; TROP1;17 1A;323/A3;35-KD glycoprotein; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; chromosome 4; CO 17A; CO17 1A; CO17A; EGP 2; EGP2; Ep CAM; EpCAM1; Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) ; Epithelial cell surface antigen; Epithelial cellular adhesion molecule; Epithelial glycoprotein; Epithelial glycoprotein 1; Epithelial glycoprotein 314; EpithelialGlycoprotein; GA733 1; GA733 2; gastrointestinal tumor-associated antigen 2; gp4; hEGP 2; hEGP314; Human epithelial glycoprotein 2; KS 1/4 antigen; KS 1/4 antigen.KSA; Ly74; Lymphocyte antigen 74; M1S 1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component; Membrane component chromosome 4 surface marker (35kD glycoprotein) ; MK 1; Protein 289A; surface marker; surface marker 1; TACD1; Tumor associated calcium signal transducer 1; Tumor associated calcium signal transducer 2 precursor; Tumor-associated calcium signal transducer 1
Clonality
Monoclonal
Clone
8C2
Conjugation
Unconjugated
Applications
WB; IHC-P; FCM; ICC/IF; IP
Field of Research
Tags & Cell Markers
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; FCM 1:100-1:500; IHC-P 1:1000-1:5000; ICC/IF 1:250-1:5000; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
40 kDa
Isotype
IgG
Available Sizes
Curated Selection
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