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Recombinant Fractalkine/CX3CL1 Monoclonal Antibody

Product Specifications

Background

This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.

Abbreviation

CX3CL1

UniProt

P78423

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Fractalkine / CX3CL1 protein

Target

CXC; ABCD; SCYD; IGHG; C-X3-C Motif Chemokine; Small-Inducible Cytokine D; CX3CL; A-152E; CX3CL1; ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; CX3C Membrane-Anchored Chemokine; C-X3-C Motif Chemokine 1; Neurotactin; Small-Inducible Cytokine D1; IGHG3; FKN; A-152E5.2; Fractalkine

Clonality

Monoclonal

Clone

7C14

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Immunology; Cardiovascular

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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