Recombinant Fractalkine/CX3CL1 Monoclonal Antibody
Product Specifications
Background
This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.
Abbreviation
CX3CL1
UniProt
P78423
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Fractalkine / CX3CL1 protein
Target
CXC; ABCD; SCYD; IGHG; C-X3-C Motif Chemokine; Small-Inducible Cytokine D; CX3CL; A-152E; CX3CL1; ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; CX3C Membrane-Anchored Chemokine; C-X3-C Motif Chemokine 1; Neurotactin; Small-Inducible Cytokine D1; IGHG3; FKN; A-152E5.2; Fractalkine
Clonality
Monoclonal
Clone
7C14
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Immunology; Cardiovascular
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:50-1:200
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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