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Recombinant IL3RA/CD123 Monoclonal Antibody

Product Specifications

Background

CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Abbreviation

IL3Ra

UniProt

P26951

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human IL3RA protein

Target

IL3RA; CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; IL-3 Receptor alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R subunitalpha; IL-3RA; IL-3R-alpha; IL-3Receptoralpha; IL-3Rα; IL-4Receptoralpha; IL-5Receptoralpha; IL-6Receptoralpha; IL-7Receptoralpha; Interleukin-3 receptor subunit alpha; IL-3R&alpha

Clonality

Monoclonal

Clone

7C8

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Immunology; Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

38 kDa

Isotype

IgG

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