Recombinant Carbonic Anhydrase III/CA3 Monoclonal Antibody
Product Specifications
Background
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.0 kb and contains seven exons and six introns.
Abbreviation
CA3
UniProt
P07451
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Carbonic Anhydrase III / CA3 protein
Target
Car; CA3; CAIII; Car3; CA-III; Carbonate Dehydratase III; Carbonic Anhydrase 3; Carbonic Anhydrase III
Clonality
Monoclonal
Clone
7C4
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Cardiovascular; Tags & Cell Markers; Cell Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 1-4 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
30 kDa
Isotype
IgG
Curated Selection
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