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Recombinant Carbonic Anhydrase III/CA3 Monoclonal Antibody

Product Specifications

Background

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.0 kb and contains seven exons and six introns.

Abbreviation

CA3

UniProt

P07451

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Carbonic Anhydrase III / CA3 protein

Target

Car; CA3; CAIII; Car3; CA-III; Carbonate Dehydratase III; Carbonic Anhydrase 3; Carbonic Anhydrase III

Clonality

Monoclonal

Clone

7C4

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Tags & Cell Markers; Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 1-4 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30 kDa

Observed Molecular Weight

30 kDa

Isotype

IgG

Curated Selection

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