Recombinant HGF Monoclonal Antibody
Product Specifications
Background
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.
Abbreviation
HGF
UniProt
P14210
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human HGF Protein
Target
DFNB; HGF; DFNB39; F-TCF; HGFB; HPTA; SF; Hepapoietin A; Hepatocyte growth factor; Hepatopoietin-A; Scatter Factor; F TCF; Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor (hepapoietin A; Hepatocyte growth factor beta chain; Hepatocyte growth factor precursor; Hepatopoietin A; Lung fibroblast derived mitogen; OTTHUMP00000161349; OTTHUMP00000206710; OTTHUMP00000206711; OTTHUMP00000206712; OTTHUMP00000206713; OTTHUMP00000206730; scatter factor)
Clonality
Monoclonal
Clone
5C7
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:50-1:200
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
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