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Recombinant HGF Monoclonal Antibody

Product Specifications

Background

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Abbreviation

HGF

UniProt

P14210

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human HGF Protein

Target

DFNB; HGF; DFNB39; F-TCF; HGFB; HPTA; SF; Hepapoietin A; Hepatocyte growth factor; Hepatopoietin-A; Scatter Factor; F TCF; Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor (hepapoietin A; Hepatocyte growth factor beta chain; Hepatocyte growth factor precursor; Hepatopoietin A; Lung fibroblast derived mitogen; OTTHUMP00000161349; OTTHUMP00000206710; OTTHUMP00000206711; OTTHUMP00000206712; OTTHUMP00000206713; OTTHUMP00000206730; scatter factor)

Clonality

Monoclonal

Clone

5C7

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Signal Transduction; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Frequently Asked Questions

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