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Recombinant Glucosamine (N-acetyl) -6-Sulfatase/G6S Monoclonal Antibody

Product Specifications

Background

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome) . Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Abbreviation

GNS

UniProt

P15586

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human GNS protein

Target

GNS; G6S; Glucosamine-6-Sulfatase; N-Acetylglucosamine-6-Sulfatase

Clonality

Monoclonal

Clone

4D5

Conjugation

Unconjugated

Applications

WB

Field of Research

Tags & Cell Markers; Signal Transduction; Cell Biology; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

62 kDa

Observed Molecular Weight

95 kDa

Isotype

IgG

Frequently Asked Questions

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