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Recombinant HNMT Monoclonal Antibody

Product Specifications

Background

In mammals, histamine is metabolized by two major pathways: N (tau) -methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) -methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Abbreviation

HNMT

UniProt

P50135

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human HNMT protein

Target

MRT; HNMT; HMT; HNMT-S1; HNMT-S2; MRT51

Clonality

Monoclonal

Clone

2D5

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Neuroscience

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 0.5-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Observed Molecular Weight

33 kDa

Isotype

IgG

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