Recombinant HNMT Monoclonal Antibody
Product Specifications
Background
In mammals, histamine is metabolized by two major pathways: N (tau) -methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) -methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Abbreviation
HNMT
UniProt
P50135
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human HNMT protein
Target
MRT; HNMT; HMT; HNMT-S1; HNMT-S2; MRT51
Clonality
Monoclonal
Clone
2D5
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Neuroscience
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 0.5-2 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
33 kDa
Observed Molecular Weight
33 kDa
Isotype
IgG
Curated Selection
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