Recombinant NQO1 Monoclonal Antibody
Product Specifications
Background
This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 1-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Abbreviation
NQO1
UniProt
P15559
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human NQO1 Protein
Target
NQO; DIA; NMOR; DHQU; DIA4; DTD; NMOR1; NMORI; QR1; NQO1; Azoreductase; Cytochrome b 5 reductase; DIA 4; Diaphorase (NADH/NADPH) ; Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) ; Diaphorase 4; Dioxin inducible 1; DT diaphorase; DT-diaphorase; Menadione reductase; NAD (P) H dehydrogenase [quinone] 1; NAD (P) H dehydrogenase quinone 1; NAD (P) H menadione oxidoreductase 1 dioxin inducible; NAD (P) H quinone dehydrogenase 1; NAD (P) H: menadione oxidoreductase 1 dioxin inducible 1; NAD (P) H:menadione oxidoreductase 1; NAD (P) H:Quinone acceptor oxidoreductase type 1; NAD (P) H:quinone oxidoreductase 1; NAD (P) H:quinone oxireductase; NMOR 1; NMOR I; NQO 1; Phylloquinone reductase; QR 1; Quinone reductase 1
Clonality
Monoclonal
Clone
5B11
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/yrtdvpqq
Product MSDS
https://789.bio/eb/6b18fK5I
Calculated Molecular Weight
31 kDa
Observed Molecular Weight
31 kDa
Isotype
IgG
Curated Selection
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