Recombinant Phospho-CrkL (Tyr207) Monoclonal Antibody
Product Specifications
Background
This gene encodes a protein kinase containing SH2 and SH0 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Abbreviation
CRKL
UniProt
P46109
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around (Tyr207) of Human Phospho-CrkL
Target
HGNC; CRKL; Crk L; Crk like protein; Crk-like protein; Crkol; HGNC:2363; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; v crk sarcoma virus CT10 oncogene homolog (avian) like; V crk sarcoma virus CT10 oncogene homolog avian like; HGNC:2363
Clonality
Monoclonal
Clone
5B9
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Epigenetics and Nuclear Signaling; Signal Transduction; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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