Recombinant Phospho-MAPKAPK-2 (Thr334) Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP24 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Abbreviation
MAPKAPK2
UniProt
P49137
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around (Thr334) of Human Phospho-MAPKAPK-2
Target
MAPKAPK; MAPKAP-K; MAPKAPK2; MAPKAP-K2; MK-2; MK2
Clonality
Monoclonal
Clone
5B4
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular; Signal Transduction
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
45 kDa;40 kDa
Isotype
IgG
Available Sizes
Curated Selection
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