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Recombinant Phospho-Bad (Ser99) Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-1, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Abbreviation

Bad

UniProt

Q92934

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the residues around Ser99 of Human Phospho-Bad

Target

BCL2L; BBC; BAD; BBC2; BCL2L8; BBC6; AI325008; BBC 2; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X/BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl-2-binding component 6; Bcl2-L-8; Bcl-2-like protein 8; Bcl-XL/Bcl-2-associated death promoter; Proapoptotic BH3 Only Protein

Clonality

Monoclonal

Clone

4B16

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:20000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

18 kDa

Observed Molecular Weight

18 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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