Recombinant Phospho-Bad (Ser99) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-1, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Abbreviation
Bad
UniProt
Q92934
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around Ser99 of Human Phospho-Bad
Target
BCL2L; BBC; BAD; BBC2; BCL2L8; BBC6; AI325008; BBC 2; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X/BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl-2-binding component 6; Bcl2-L-8; Bcl-2-like protein 8; Bcl-XL/Bcl-2-associated death promoter; Proapoptotic BH3 Only Protein
Clonality
Monoclonal
Clone
4B16
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:20000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
18 kDa
Observed Molecular Weight
18 kDa
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items