Recombinant Phospho-GSK3 beta (Ser9) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
GSK3B
UniProt
P49841
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues around Ser9 of Human Phospho-GSK3 beta
Target
GSK3B; gsk-3β; Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3B; glycogen synthase kinase-3 beta
Clonality
Monoclonal
Clone
4B10
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cardiovascular; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
50 kDa
Isotype
IgG
Available Sizes
Curated Selection
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