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Recombinant Phospho-GSK3 beta (Ser9) Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

GSK3B

UniProt

P49841

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to residues around Ser9 of Human Phospho-GSK3 beta

Target

GSK3B; gsk-3β; Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3beta isoform; Serine/threonine-protein kinase GSK3B; glycogen synthase kinase-3 beta

Clonality

Monoclonal

Clone

4B10

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cardiovascular; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

46 kDa

Observed Molecular Weight

50 kDa

Isotype

IgG

Available Sizes

Curated Selection

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