Recombinant Phospho-mTOR (Ser2448) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Abbreviation
MTOR
UniProt
P42345
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR
Target
RAFT; RAPT; FK506 binding protein 12-rapamycin associated protein; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; mTOR; FK506 binding protein 12-rapamycin associated protein 1; Mechanistic target of rapamycin; dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1) ; FK506 binding protein 12 rapamycin associated protein 1; FK506 binding protein 12 rapamycin associated protein 2; FK506 binding protein 12 rapamycin complex associated protein 1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP rapamycin associated protein; FKBP12 rapamycin complex associated protein; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FLJ44809; Mammalian target of rapamycin; OTTHUMP00000001983; Rapamycin and FKBP12 target 1; Rapamycin associated protein FRAP2; Rapamycin target protein; Rapamycin target protein 1; Serine/threonine-protein kinase mTOR
Clonality
Monoclonal
Clone
4B9
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Kits; Lysates; Other; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:2000-1:20000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
280 kDa
Observed Molecular Weight
288 kDa
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items