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Recombinant GFAP Monoclonal Antibody

Product Specifications

Background

GFAP (Glial fibrillary acidic protein) is a type III intermediate filament protein. It is the major component of astrocyte intermediate filament. Defects in GFAP are a cause of Alexander disease. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. At the amino acid sequence level, human GFAP shares 91% and 90% identity with rat and mouse GFAP, respectively.

Abbreviation

GFAP

UniProt

P14136

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the center region of the human GFAP

Target

ZGC; etID36982; wu:fb34h; wu:fk42c; ALXDRD; GFAP; cb345; etID36982.3; FLJ42474; FLJ45472; gfapl; Glial Fibrillary Acidic Protein; Intermediate Filament Protein; wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; wu:fb34h11; ALXDRD; cb345; etID36982.3; FLJ42474; FLJ45472; GFAP; GFAP; gfapl; Glial fibrillary acidic protein; Intermediate filament protein; wu:fk42c12; xx:af506734; zgc:110485

Clonality

Monoclonal

Clone

4B2

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction; Tags & Cell Markers; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50 kDa

Observed Molecular Weight

45 kDa

Isotype

IgG

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