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Recombinant Olig-2/Oligo2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14;21) (q11.2; q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 18 which has been suggested to play a role in learning deficits associated with Down syndrome.

Abbreviation

OLIG2

UniProt

Q13516

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human Olig-2.

Target

OLIG; RACK; BHLHB; OLIGO; bHLHe; PRKCBP; OLIG2; BHLHB1; OLIGO2; PRKCBP2; RACK17; bHLHe19

Clonality

Monoclonal

Clone

3G12

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

32 kDa

Observed Molecular Weight

37 kDa

Isotype

IgG

Available Sizes

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