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Recombinant Sox2 Monoclonal Antibody

Product Specifications

Background

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .

Abbreviation

Sox2

UniProt

P48431

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the N-terminus of the human Sox2.

Target

SOX; ANOP; MCOPS; SRY-box; ANOP3; MCOPS3; SOX2; SRY-box 2; cb236; Delta EF2a; lcc; MGC148683; MGC2413; RGD1565646; Sex determining region Y box 2; SOX 2; SRY (sex determining region Y) box 2; SRY box containing gene 2; SRY related HMG box 2; SRY related HMG box gene 2; Transcription factor SOX 2; Transcription factor SOX-2; ysb; ANOP3; MCOPS3; Sox2; SRY-box 2

Clonality

Monoclonal

Clone

3G4

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

34 kDa

Observed Molecular Weight

37 kDa

Isotype

IgG

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