Recombinant Sox2 Monoclonal Antibody
Product Specifications
Background
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) .
Abbreviation
Sox2
UniProt
P48431
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the N-terminus of the human Sox2.
Target
SOX; ANOP; MCOPS; SRY-box; ANOP3; MCOPS3; SOX2; SRY-box 2; cb236; Delta EF2a; lcc; MGC148683; MGC2413; RGD1565646; Sex determining region Y box 2; SOX 2; SRY (sex determining region Y) box 2; SRY box containing gene 2; SRY related HMG box 2; SRY related HMG box gene 2; Transcription factor SOX 2; Transcription factor SOX-2; ysb; ANOP3; MCOPS3; Sox2; SRY-box 2
Clonality
Monoclonal
Clone
3G4
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
37 kDa
Isotype
IgG
Curated Selection
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