Recombinant Phospho-CREB (Ser133) Monoclonal Antibody

Product Specifications

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

Abbreviation

CREB1

UniProt

P16220

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues around Ser133 of human CREB.

Target

CREB1; CREB; CREB-1; Active transcription factor CREB; cAMP response element binding protein; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein

Clonality

Monoclonal

Clone

9D15

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Epigenetics and Nuclear Signaling; Immunology; Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:10000-1:200000; IHC-P 1:100-1:500

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.